ENSMUSG00000027067


Mus musculus

Features
Gene ID: ENSMUSG00000027067
  
Biological name :Ssrp1
  
Synonyms : FACT complex subunit SSRP1 / Q08943 / Ssrp1
  
Possible biological names infered from orthology : Q08945 / structure specific recognition protein 1
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: D
Gene start: 85037234
Gene end: 85047109
  
Corresponding Affymetrix probe sets: 10473414 (MoGene1.0st)   1426788_a_at (Mouse Genome 430 2.0 Array)   1426789_s_at (Mouse Genome 430 2.0 Array)   1426790_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076971
Ensembl peptide - ENSMUSP00000121639
Ensembl peptide - ENSMUSP00000127058
NCBI entrez gene - 20833     See in Manteia.
MGI - MGI:107912
RefSeq - XM_006499070
RefSeq - NM_001136081
RefSeq - NM_182990
RefSeq Peptide - NP_001129553
RefSeq Peptide - NP_892035
swissprot - Q08943
swissprot - A2AW05
Ensembl - ENSMUSG00000027067
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ssrp1aENSDARG00000037397Danio rerio
 ssrp1bENSDARG00000016994Danio rerio
 SSRP1ENSGALG00000007520Gallus gallus
 SSRP1ENSG00000149136Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tox2 / TOX high mobility group box family member 2 / Q96NM4*ENSMUSG0000007460713
Tox / Q66JW3 / Thymocyte selection-associated high mobility group box protein TOX / O94900* / thymocyte selection associated high mobility group box*ENSMUSG0000004127213
Tox4 / Q8BU11 / TOX high mobility group box family member 4 / O94842*ENSMUSG0000001683113
Tox3 / Q80W03 / TOX high mobility group box family member 3 / O15405*ENSMUSG0000004366813


Protein motifs (from Interpro)
Interpro ID Name
 IPR000969  Structure-specific recognition protein
 IPR009071  High mobility group box domain
 IPR011993  PH-like domain superfamily
 IPR013719  Domain of unknown function DUF1747
 IPR024954  SSRP1 domain
 IPR035417  FACT complex subunit POB3-like, N-terminal PH domain
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004965 inner cell mass degeneration 
Show

Allelic Composition: Pdgfbtm3.1Cbet/Pdgfbtm3.1Cbet
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Pdgfbtm3.1Cbet/Pdgfbtm3.1Cbet
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024387 Csnk2b / P67871 / Casein kinase II subunit beta / P67870* / casein kinase 2 beta*  / complex / reaction
 ENSMUSG00000046707 O54833 / Csnk2a2 / Casein kinase II subunit alpha / P19784* / casein kinase 2 alpha 2*  / reaction / complex
 ENSMUSG00000035726 Supt16 / suppressor of Ty 16 / Q9Y5B9* / SUPT16H* / SPT16 homolog, facilitates chromatin remodeling subunit*  / complex / reaction
 ENSMUSG00000101523 Q60737 / Gm10031 / predicted pseudogene 10031 / Q8NEV1* / P68400* / CSNK2A1* / CSNK2A3* / casein kinase 2 alpha 1* / casein kinase 2 alpha 3*  / complex / reaction






 

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contact: otassy@igbmc.fr