ENSG00000124571


Homo sapiens

Features
Gene ID: ENSG00000124571
  
Biological name :XPO5
  
Synonyms : exportin 5 / Q9HAV4 / XPO5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.1
Gene start: 43522330
Gene end: 43576075
  
Corresponding Affymetrix probe sets: 223055_s_at (Human Genome U133 Plus 2.0 Array)   223056_s_at (Human Genome U133 Plus 2.0 Array)   223057_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387384
Ensembl peptide - ENSP00000426185
Ensembl peptide - ENSP00000424196
Ensembl peptide - ENSP00000265351
Ensembl peptide - ENSP00000381779
Ensembl peptide - ENSP00000381816
NCBI entrez gene - 57510     See in Manteia.
OMIM - 607845
RefSeq - NM_020750
RefSeq Peptide - NP_065801
swissprot - H0Y9I3
swissprot - H0YA57
swissprot - E2QRM3
swissprot - Q9HAV4
swissprot - H0Y3Q8
swissprot - H0Y3W3
Ensembl - ENSG00000124571
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01087629.1ENSDARG00000112522Danio rerio
 XPO5ENSDARG00000098868Danio rerio
 XPO5ENSGALG00000010341Gallus gallus
 Xpo5ENSMUSG00000067150Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR013598  Exportin-1/Importin-beta-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006611 protein export from nucleus IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0010586 miRNA metabolic process TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0035281 pre-miRNA export from nucleus NAS
 biological_processGO:0046825 regulation of protein export from nucleus IBA
 biological_processGO:1900370 positive regulation of RNA interference IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0035068 micro-ribonucleoprotein complex IDA
 cellular_componentGO:0042272 nuclear RNA export factor complex IDA
 cellular_componentGO:0042565 RNA nuclear export complex IDA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0005049 nuclear export signal receptor activity IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008536 Ran GTPase binding IPI
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:0070883 pre-miRNA binding NAS
 molecular_functionGO:0140142 nucleocytoplasmic carrier activity IMP


Pathways (from Reactome)
Pathway description
MicroRNA (miRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132341 RAN / P62826 / RAN, member RAS oncogene family  / complex






 

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