ENSG00000124659


Homo sapiens

Features
Gene ID: ENSG00000124659
  
Biological name :TBCC
  
Synonyms : Q15814 / TBCC / tubulin folding cofactor C
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.1
Gene start: 42744481
Gene end: 42746096
  
Corresponding Affymetrix probe sets: 202495_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361967
NCBI entrez gene - 6903     See in Manteia.
OMIM - 602971
RefSeq - NM_003192
RefSeq Peptide - NP_003183
swissprot - Q15814
Ensembl - ENSG00000124659
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbccENSDARG00000022918Danio rerio
 TbccENSMUSG00000036430Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RP2 / O75695 / RP2, ARL3 GTPase activating proteinENSG0000010221816


Protein motifs (from Interpro)
Interpro ID Name
 IPR006599  CARP motif
 IPR012945  Tubulin binding cofactor C-like domain
 IPR017901  C-CAP/cofactor C-like domain
 IPR027684  Tubulin-specific chaperone C
 IPR031925  Tubulin-specific chaperone C, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0007021 tubulin complex assembly IBA
 biological_processGO:0007023 post-chaperonin tubulin folding pathway TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005874 microtubule TAS
 cellular_componentGO:0032391 photoreceptor connecting cilium IDA
 molecular_functionGO:0003924 GTPase activity IDA
 molecular_functionGO:0015631 tubulin binding IEA
 molecular_functionGO:0051087 chaperone binding TAS


Pathways (from Reactome)
Pathway description
Post-chaperonin tubulin folding pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141556 TBCD / Q9BTW9 / tubulin folding cofactor D  / reaction / complex
 ENSG00000284770 TBCE / Q15813 / tubulin folding cofactor E  / reaction / complex






 

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