ENSG00000124767


Homo sapiens

Features
Gene ID: ENSG00000124767
  
Biological name :GLO1
  
Synonyms : GLO1 / glyoxalase I / Q04760
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.2
Gene start: 38675925
Gene end: 38703141
  
Corresponding Affymetrix probe sets: 200681_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362463
NCBI entrez gene - 2739     See in Manteia.
OMIM - 138750
RefSeq - NM_006708
RefSeq Peptide - NP_006699
swissprot - Q04760
swissprot - X5DNM4
Ensembl - ENSG00000124767
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glo1ENSDARG00000068978Danio rerio
 GLO1ENSGALG00000010127Gallus gallus
 Glo1ENSMUSG00000024026Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004360  Glyoxalase/fosfomycin resistance/dioxygenase domain
 IPR004361  Glyoxalase I
 IPR018146  Glyoxalase I, conserved site
 IPR029068  Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
 IPR037523  Vicinal oxygen chelate (VOC) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006090 pyruvate metabolic process TAS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0009438 methylglyoxal metabolic process IEA
 biological_processGO:0030316 osteoclast differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004462 lactoylglutathione lyase activity TAS
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000124767 GLO1 / Q04760 / glyoxalase I  / complex






 

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