ENSG00000124789


Homo sapiens

Features
Gene ID: ENSG00000124789
  
Biological name :NUP153
  
Synonyms : nucleoporin 153 / NUP153 / P49790
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p22.3
Gene start: 17615035
Gene end: 17706834
  
Corresponding Affymetrix probe sets: 202097_at (Human Genome U133 Plus 2.0 Array)   239948_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262077
Ensembl peptide - ENSP00000444029
Ensembl peptide - ENSP00000478627
NCBI entrez gene - 9972     See in Manteia.
OMIM - 603948
RefSeq - XM_017011594
RefSeq - NM_001278209
RefSeq - NM_001278210
RefSeq - NM_005124
RefSeq - XM_005249507
RefSeq - XM_006715290
RefSeq - XM_006715291
RefSeq - XM_011515028
RefSeq Peptide - NP_001265139
RefSeq Peptide - NP_005115
RefSeq Peptide - NP_001265138
swissprot - P49790
Ensembl - ENSG00000124789
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup153ENSDARG00000099972Danio rerio
 NUP153ENSGALG00000012720Gallus gallus
 Nup153ENSMUSG00000021374Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001876  Zinc finger, RanBP2-type
 IPR013913  Nucleoporin Nup153, N-terminal
 IPR018892  Retro-transposon transporting motif
 IPR026054  Nuclear pore complex protein
 IPR036443  Zinc finger, RanBP2-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0046832 negative regulation of RNA export from nucleus IDA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0051292 nuclear pore complex assembly IMP
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075732 viral penetration into host nucleus IEA
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0034399 nuclear periphery IDA
 cellular_componentGO:0042405 nuclear inclusion body IDA
 cellular_componentGO:0043657 host cell IEA
 cellular_componentGO:0044615 nuclear pore nuclear basket IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0017056 structural constituent of nuclear pore IMP
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043495 protein membrane anchor IMP
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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