ENSG00000125484


Homo sapiens

Features
Gene ID: ENSG00000125484
  
Biological name :GTF3C4
  
Synonyms : general transcription factor IIIC subunit 4 / GTF3C4 / Q9UKN8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.13
Gene start: 132670035
Gene end: 132694955
  
Corresponding Affymetrix probe sets: 219198_at (Human Genome U133 Plus 2.0 Array)   225543_at (Human Genome U133 Plus 2.0 Array)   243228_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361219
Ensembl peptide - ENSP00000431378
NCBI entrez gene - 9329     See in Manteia.
OMIM - 604892
RefSeq - XM_017015318
RefSeq - NM_012204
RefSeq Peptide - NP_036336
swissprot - Q9UKN8
swissprot - F2Z356
Ensembl - ENSG00000125484
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf3c4ENSDARG00000069538Danio rerio
 GTF3C4ENSGALG00000031016Gallus gallus
 Gtf3c4ENSMUSG00000035666Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR024761  Transcription factor IIIC, 90kDa subunit, N-terminal
 IPR024764  Transcription factor IIIC, putative zinc-finger
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IC
 biological_processGO:0006383 transcription by RNA polymerase III IC
 biological_processGO:0006384 transcription initiation from RNA polymerase III promoter TAS
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0042791 5S class rRNA transcription by RNA polymerase III IC
 biological_processGO:0042797 tRNA transcription by RNA polymerase III IC
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0000127 transcription factor TFIIIC complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0003677 DNA binding IC
 molecular_functionGO:0004402 histone acetyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008047 enzyme activator activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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