ENSG00000125731


Homo sapiens

Features
Gene ID: ENSG00000125731
  
Biological name :SH2D3A
  
Synonyms : Q9BRG2 / SH2D3A / SH2 domain containing 3A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 6752160
Gene end: 6767588
  
Corresponding Affymetrix probe sets: 219513_s_at (Human Genome U133 Plus 2.0 Array)   222169_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000245908
Ensembl peptide - ENSP00000393303
Ensembl peptide - ENSP00000470700
NCBI entrez gene - 10045     See in Manteia.
OMIM - 604721
RefSeq - XM_017026124
RefSeq - NM_005490
RefSeq - XM_011527608
RefSeq - XM_011527609
RefSeq - XM_017026123
RefSeq - XM_005259467
RefSeq - XM_005259472
RefSeq - XM_006722602
RefSeq Peptide - NP_005481
swissprot - Q9BRG2
swissprot - M0QZQ6
Ensembl - ENSG00000125731
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01115881.1ENSDARG00000086539Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCAR3 / O75815 / BCAR3, NSP family adaptor proteinENSG0000013793639
Q8N5H7 / SH2D3C / SH2 domain containing 3CENSG0000009537035


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR036860  SH2 domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity TAS
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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