ENSG00000137936


Homo sapiens

Features
Gene ID: ENSG00000137936
  
Biological name :BCAR3
  
Synonyms : BCAR3 / BCAR3, NSP family adaptor protein / O75815
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.1
Gene start: 93561786
Gene end: 93847150
  
Corresponding Affymetrix probe sets: 204032_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359264
Ensembl peptide - ENSP00000260502
Ensembl peptide - ENSP00000359263
Ensembl peptide - ENSP00000359267
Ensembl peptide - ENSP00000441343
NCBI entrez gene - 8412     See in Manteia.
OMIM - 604704
RefSeq - XM_017002480
RefSeq - NM_001261408
RefSeq - NM_001261409
RefSeq - NM_001261410
RefSeq - NM_001308251
RefSeq - NM_003567
RefSeq - XM_011542251
RefSeq Peptide - NP_001248339
RefSeq Peptide - NP_001295180
RefSeq Peptide - NP_003558
RefSeq Peptide - NP_001248337
RefSeq Peptide - NP_001248338
swissprot - O75815
Ensembl - ENSG00000137936
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bcar3ENSDARG00000016981Danio rerio
 Bcar3ENSMUSG00000028121Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8N5H7 / SH2D3C / SH2 domain containing 3CENSG0000009537039
Q9BRG2 / SH2D3A / SH2 domain containing 3AENSG0000012573127


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR028849  Breast cancer anti-estrogen resistance protein 3
 IPR036860  SH2 domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002089 lens morphogenesis in camera-type eye IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0042493 response to drug TAS
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IBA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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