ENSG00000095370


Homo sapiens

Features
Gene ID: ENSG00000095370
  
Biological name :SH2D3C
  
Synonyms : Q8N5H7 / SH2D3C / SH2 domain containing 3C
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.11
Gene start: 127738317
Gene end: 127778741
  
Corresponding Affymetrix probe sets: 1552667_a_at (Human Genome U133 Plus 2.0 Array)   215639_at (Human Genome U133 Plus 2.0 Array)   226673_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000485866
Ensembl peptide - ENSP00000401641
Ensembl peptide - ENSP00000413760
Ensembl peptide - ENSP00000317817
Ensembl peptide - ENSP00000362373
Ensembl peptide - ENSP00000362374
Ensembl peptide - ENSP00000388536
Ensembl peptide - ENSP00000394632
NCBI entrez gene - 10044     See in Manteia.
OMIM - 604722
RefSeq - XM_017014174
RefSeq - NM_001142531
RefSeq - NM_001142532
RefSeq - NM_001142533
RefSeq - NM_001142534
RefSeq - NM_001252334
RefSeq - NM_005489
RefSeq - NM_170600
RefSeq - XM_005251639
RefSeq - XM_011518114
RefSeq - XM_011518115
RefSeq - XM_011518117
RefSeq Peptide - NP_001239263
RefSeq Peptide - NP_005480
RefSeq Peptide - NP_733745
RefSeq Peptide - NP_001136004
RefSeq Peptide - NP_001136005
RefSeq Peptide - NP_001136006
RefSeq Peptide - NP_001136003
swissprot - Q5JU32
swissprot - Q8N5H7
swissprot - H0Y5X5
Ensembl - ENSG00000095370
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh2d3caENSDARG00000028099Danio rerio
 sh2d3cbENSDARG00000104555Danio rerio
 SH2D3CENSGALG00000005036Gallus gallus
 Q9QZS8ENSMUSG00000059013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCAR3 / O75815 / BCAR3, NSP family adaptor proteinENSG0000013793638
Q9BRG2 / SH2D3A / SH2 domain containing 3AENSG0000012573123


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR036860  SH2 domain superfamily
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity TAS
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr