ENSG00000126216


Homo sapiens

Features
Gene ID: ENSG00000126216
  
Biological name :TUBGCP3
  
Synonyms : Q96CW5 / TUBGCP3 / tubulin gamma complex associated protein 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q34
Gene start: 112485005
Gene end: 112588167
  
Corresponding Affymetrix probe sets: 1554086_at (Human Genome U133 Plus 2.0 Array)   203690_at (Human Genome U133 Plus 2.0 Array)   215739_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478276
Ensembl peptide - ENSP00000482912
Ensembl peptide - ENSP00000261965
Ensembl peptide - ENSP00000364821
NCBI entrez gene - 10426     See in Manteia.
OMIM - 617818
RefSeq - XM_017020323
RefSeq - NM_001286278
RefSeq - NM_001286279
RefSeq - NM_006322
RefSeq - XM_005268293
RefSeq - XM_011537462
RefSeq - XM_011537463
RefSeq - XM_011537464
RefSeq - NM_001286277
RefSeq Peptide - NP_006313
RefSeq Peptide - NP_001273206
RefSeq Peptide - NP_001273207
RefSeq Peptide - NP_001273208
swissprot - Q96CW5
swissprot - A0A087WZV5
swissprot - A0A087WU06
Ensembl - ENSG00000126216
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tubgcp3ENSDARG00000029133Danio rerio
 TUBGCP3ENSGALG00000016836Gallus gallus
 P58854ENSMUSG00000000759Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96RT7 / TUBGCP6 / tubulin gamma complex associated protein 6ENSG0000012815923
Q9BSJ2 / TUBGCP2 / tubulin gamma complex associated protein 2ENSG0000013064018
Q96RT8 / TUBGCP5 / tubulin gamma complex associated protein 5ENSG0000027583517
Q9UGJ1 / TUBGCP4 / tubulin gamma complex associated protein 4ENSG0000013782211


Protein motifs (from Interpro)
Interpro ID Name
 IPR007259  Gamma-tubulin complex component protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0007020 microtubule nucleation IEA
 biological_processGO:0007338 single fertilization NAS
 biological_processGO:0031122 cytoplasmic microtubule organization IBA
 biological_processGO:0051298 centrosome duplication IBA
 biological_processGO:0051321 meiotic cell cycle IBA
 biological_processGO:0051415 microtubule nucleation by interphase microtubule organizing center IBA
 biological_processGO:0090307 mitotic spindle assembly IBA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0000923 equatorial microtubule organizing center IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome NAS
 cellular_componentGO:0005814 centriole IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle NAS
 cellular_componentGO:0005827 polar microtubule IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0008275 gamma-tubulin small complex IBA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0005198 structural molecule activity NAS
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043015 gamma-tubulin binding IEA
 molecular_functionGO:0051011 microtubule minus-end binding IBA


Pathways (from Reactome)
Pathway description
Recruitment of mitotic centrosome proteins and complexes
Recruitment of NuMA to mitotic centrosomes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131462 TUBG1 / P23258 / tubulin gamma 1  / complex
 ENSG00000037042 TUBG2 / Q9NRH3 / tubulin gamma 2  / complex
 ENSG00000130640 Q9BSJ2 / TUBGCP2 / tubulin gamma complex associated protein 2  / complex






 

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