ENSG00000130640


Homo sapiens

Features
Gene ID: ENSG00000130640
  
Biological name :TUBGCP2
  
Synonyms : Q9BSJ2 / TUBGCP2 / tubulin gamma complex associated protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q26.3
Gene start: 133278630
Gene end: 133312337
  
Corresponding Affymetrix probe sets: 202476_s_at (Human Genome U133 Plus 2.0 Array)   202477_s_at (Human Genome U133 Plus 2.0 Array)   213563_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446093
Ensembl peptide - ENSP00000436438
Ensembl peptide - ENSP00000473262
Ensembl peptide - ENSP00000252936
Ensembl peptide - ENSP00000357550
Ensembl peptide - ENSP00000357551
Ensembl peptide - ENSP00000395666
NCBI entrez gene - 10844     See in Manteia.
OMIM - 617817
RefSeq - XM_017015596
RefSeq - NM_001256617
RefSeq - NM_001256618
RefSeq - NM_006659
RefSeq - XM_017015595
RefSeq Peptide - NP_001243546
RefSeq Peptide - NP_001243547
RefSeq Peptide - NP_006650
swissprot - F2Z2B9
swissprot - Q9BSJ2
swissprot - R4GMM4
swissprot - B3KTU7
Ensembl - ENSG00000130640
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tubgcp2ENSDARG00000013079Danio rerio
 TUBGCP2ENSGALG00000003526Gallus gallus
 Q921G8ENSMUSG00000025474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96RT7 / TUBGCP6 / tubulin gamma complex associated protein 6ENSG0000012815922
Q96CW5 / TUBGCP3 / tubulin gamma complex associated protein 3ENSG0000012621618
Q96RT8 / TUBGCP5 / tubulin gamma complex associated protein 5ENSG0000027583514
Q9UGJ1 / TUBGCP4 / tubulin gamma complex associated protein 4ENSG0000013782212


Protein motifs (from Interpro)
Interpro ID Name
 IPR007259  Gamma-tubulin complex component protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0007020 microtubule nucleation TAS
 biological_processGO:0031122 cytoplasmic microtubule organization IBA
 biological_processGO:0051298 centrosome duplication IBA
 biological_processGO:0051321 meiotic cell cycle IBA
 biological_processGO:0051415 microtubule nucleation by interphase microtubule organizing center IBA
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0090307 mitotic spindle assembly IBA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0000923 equatorial microtubule organizing center IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005881 cytoplasmic microtubule TAS
 cellular_componentGO:0008275 gamma-tubulin small complex IBA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043015 gamma-tubulin binding IBA
 molecular_functionGO:0051011 microtubule minus-end binding IBA


Pathways (from Reactome)
Pathway description
Recruitment of mitotic centrosome proteins and complexes
Recruitment of NuMA to mitotic centrosomes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131462 TUBG1 / P23258 / tubulin gamma 1  / complex
 ENSG00000037042 TUBG2 / Q9NRH3 / tubulin gamma 2  / complex
 ENSG00000126216 Q96CW5 / TUBGCP3 / tubulin gamma complex associated protein 3  / complex






 

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