ENSG00000127511


Homo sapiens

Features
Gene ID: ENSG00000127511
  
Biological name :SIN3B
  
Synonyms : O75182 / SIN3B / SIN3 transcription regulator family member B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.11
Gene start: 16829400
Gene end: 16880353
  
Corresponding Affymetrix probe sets: 209352_s_at (Human Genome U133 Plus 2.0 Array)   242129_at (Human Genome U133 Plus 2.0 Array)   39705_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000369131
Ensembl peptide - ENSP00000472365
Ensembl peptide - ENSP00000473039
Ensembl peptide - ENSP00000248054
Ensembl peptide - ENSP00000469740
NCBI entrez gene - 23309     See in Manteia.
OMIM - 607777
RefSeq - XM_006722704
RefSeq - NM_001297595
RefSeq - NM_001297597
RefSeq - NM_015260
RefSeq Peptide - NP_001284524
RefSeq Peptide - NP_001284526
RefSeq Peptide - NP_056075
swissprot - M0QYC5
swissprot - M0R271
swissprot - O75182
Ensembl - ENSG00000127511
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sin3bENSDARG00000062472Danio rerio
 SIN3BENSGALG00000003771Gallus gallus
 Sin3bENSMUSG00000031622Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIN3A / Q96ST3 / SIN3 transcription regulator family member AENSG0000016937552


Protein motifs (from Interpro)
Interpro ID Name
 IPR003822  Paired amphipathic helix
 IPR013194  Histone deacetylase interacting domain
 IPR031693  Sin3, C-terminal
 IPR036600  Paired amphipathic helix superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016575 histone deacetylation IBA
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0000805 X chromosome IEA
 cellular_componentGO:0000806 Y chromosome IEA
 cellular_componentGO:0001741 XY body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016580 Sin3 complex IBA
 cellular_componentGO:0030849 autosome IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0004407 histone deacetylase activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
NoRC negatively regulates rRNA expression
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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