ENSG00000127920


Homo sapiens

Features
Gene ID: ENSG00000127920
  
Biological name :GNG11
  
Synonyms : GNG11 / G protein subunit gamma 11 / P61952
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q21.3
Gene start: 93921699
Gene end: 93928610
  
Corresponding Affymetrix probe sets: 204115_at (Human Genome U133 Plus 2.0 Array)   239942_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000248564
NCBI entrez gene - 2791     See in Manteia.
OMIM - 604390
RefSeq - NM_004126
RefSeq Peptide - NP_004117
swissprot - P61952
swissprot - Q53Y01
Ensembl - ENSG00000127920
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gngt1ENSDARG00000035798Danio rerio
 GNG11ENSGALG00000029899Gallus gallus
 Gng11ENSMUSG00000032766Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GNGT1 / P63211 / G protein subunit gamma transducin 1ENSG0000012792877
GNGT2 / O14610 / G protein subunit gamma transducin 2ENSG0000016708359


Protein motifs (from Interpro)
Interpro ID Name
 IPR001770  G-protein, gamma subunit
 IPR015898  G-protein gamma-like domain
 IPR036284  G-protein gamma-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0071377 cellular response to glucagon stimulus TAS
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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