ENSG00000167083


Homo sapiens

Features
Gene ID: ENSG00000167083
  
Biological name :GNGT2
  
Synonyms : GNGT2 / G protein subunit gamma transducin 2 / O14610
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 49202791
Gene end: 49210574
  
Corresponding Affymetrix probe sets: 235139_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423924
Ensembl peptide - ENSP00000422879
Ensembl peptide - ENSP00000426022
Ensembl peptide - ENSP00000300406
Ensembl peptide - ENSP00000420946
Ensembl peptide - ENSP00000421710
NCBI entrez gene - 2793     See in Manteia.
OMIM - 139391
RefSeq - NM_001198754
RefSeq - NM_001198755
RefSeq - NM_001198756
RefSeq - NM_031498
RefSeq Peptide - NP_001185683
RefSeq Peptide - NP_001185684
RefSeq Peptide - NP_001185685
RefSeq Peptide - NP_113686
swissprot - O14610
swissprot - D6RDH5
Ensembl - ENSG00000167083
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gngt2aENSDARG00000010680Danio rerio
 gngt2bENSDARG00000103543Danio rerio
 GNGT2ENSGALG00000031205Gallus gallus
 Gngt2ENSMUSG00000038811Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GNG11 / P61952 / G protein subunit gamma 11ENSG0000012792062
GNGT1 / P63211 / G protein subunit gamma transducin 1ENSG0000012792862


Protein motifs (from Interpro)
Interpro ID Name
 IPR001770  G-protein, gamma subunit
 IPR015898  G-protein gamma-like domain
 IPR036284  G-protein gamma-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway NAS
 biological_processGO:0007602 phototransduction NAS
 cellular_componentGO:0005834 heterotrimeric G-protein complex NAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003924 GTPase activity IDA
 molecular_functionGO:0004871 obsolete signal transducer activity NAS


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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