ENSMUSG00000038811


Mus musculus

Features
Gene ID: ENSMUSG00000038811
  
Biological name :Gngt2
  
Synonyms : Gngt2 / guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 / Q61017
  
Possible biological names infered from orthology : G protein subunit gamma transducin 2 / O14610
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 95837216
Gene end: 95845734
  
Corresponding Affymetrix probe sets: 10380571 (MoGene1.0st)   1428733_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103342
Ensembl peptide - ENSMUSP00000103339
Ensembl peptide - ENSMUSP00000103340
Ensembl peptide - ENSMUSP00000047586
Ensembl peptide - ENSMUSP00000098101
Ensembl peptide - ENSMUSP00000103336
Ensembl peptide - ENSMUSP00000103337
NCBI entrez gene - 14710     See in Manteia.
MGI - MGI:893584
RefSeq - XM_017314274
RefSeq - NM_001038664
RefSeq - NM_001284393
RefSeq - NM_001284397
RefSeq - NM_023121
RefSeq - XM_006532231
RefSeq - XM_011248737
RefSeq Peptide - NP_001271326
RefSeq Peptide - NP_075610
RefSeq Peptide - NP_001033753
RefSeq Peptide - NP_001271322
swissprot - Q61017
swissprot - A2A614
Ensembl - ENSMUSG00000038811
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gngt2aENSDARG00000010680Danio rerio
 gngt2bENSDARG00000103543Danio rerio
 GNGT2ENSGALG00000031205Gallus gallus
 GNGT2ENSG00000167083Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gng11 / P61953 / guanine nucleotide binding protein (G protein), gamma 11 / P61952* / G protein subunit gamma 11*ENSMUSG0000003276664
Gngt1 / Q61012 / guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 / P63211* / G protein subunit gamma transducin 1*ENSMUSG0000002966359


Protein motifs (from Interpro)
Interpro ID Name
 IPR001770  G-protein, gamma subunit
 IPR015898  G-protein gamma-like domain
 IPR036284  G-protein gamma-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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