ENSG00000128165


Homo sapiens

Features
Gene ID: ENSG00000128165
  
Biological name :ADM2
  
Synonyms : ADM2 / adrenomedullin 2 / Q7Z4H4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.33
Gene start: 50481556
Gene end: 50486440
  
Corresponding Affymetrix probe sets: 220538_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379086
Ensembl peptide - ENSP00000379087
NCBI entrez gene - 79924     See in Manteia.
OMIM - 608682
RefSeq - XM_017028940
RefSeq - NM_001253845
RefSeq Peptide - NP_001240774
swissprot - Q7Z4H4
Ensembl - ENSG00000128165
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adm2aENSDARG00000045708Danio rerio
 adm2bENSDARG00000078875Danio rerio
 Adm2ENSMUSG00000054136Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021116  Calcitonin/adrenomedullin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007586 digestion IEA
 biological_processGO:0007631 feeding behavior IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0045766 positive regulation of angiogenesis IDA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IDA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131477 RAMP2 / O60895 / receptor activity modifying protein 2  / complex / reaction
 ENSG00000064989 CALCRL / Q16602 / calcitonin receptor like receptor  / reaction / complex
 ENSG00000122679 RAMP3 / O60896 / receptor activity modifying protein 3  / reaction / complex






 

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contact: otassy@igbmc.fr