ENSG00000122679


Homo sapiens

Features
Gene ID: ENSG00000122679
  
Biological name :RAMP3
  
Synonyms : O60896 / RAMP3 / receptor activity modifying protein 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p13
Gene start: 45157791
Gene end: 45186302
  
Corresponding Affymetrix probe sets: 205326_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000242249
Ensembl peptide - ENSP00000419012
Ensembl peptide - ENSP00000418460
NCBI entrez gene - 10268     See in Manteia.
OMIM - 605155
RefSeq - NM_005856
RefSeq Peptide - NP_005847
swissprot - A4D2L1
swissprot - J3KR56
swissprot - O60896
Ensembl - ENSG00000122679
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAMP3ENSGALG00000037246Gallus gallus
 Ramp3ENSMUSG00000041046Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAMP1 / O60894 / receptor activity modifying protein 1ENSG0000013232930
RAMP2 / O60895 / receptor activity modifying protein 2ENSG0000013147729


Protein motifs (from Interpro)
Interpro ID Name
 IPR006985  Receptor activity modifying protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001921 positive regulation of receptor recycling IDA
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IPI
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0010628 positive regulation of gene expression IGI
 biological_processGO:0010739 positive regulation of protein kinase A signaling IGI
 biological_processGO:0010942 positive regulation of cell death IGI
 biological_processGO:0015031 protein transport IDA
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process IGI
 biological_processGO:0031623 receptor internalization IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IGI
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0051897 positive regulation of protein kinase B signaling IGI
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IGI
 biological_processGO:0071392 cellular response to estradiol stimulus ISS
 biological_processGO:0072659 protein localization to plasma membrane IDA
 biological_processGO:0086103 G-protein coupled receptor signaling pathway involved in heart process ISS
 biological_processGO:0097647 amylin receptor signaling pathway IGI
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IDA
 biological_processGO:1905665 positive regulation of calcium ion import across plasma membrane IGI
 biological_processGO:1990410 adrenomedullin receptor signaling pathway IPI
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005764 lysosome TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:1903143 adrenomedullin receptor complex IDA
 cellular_componentGO:1903440 amylin receptor complex IDA
 molecular_functionGO:0001605 adrenomedullin receptor activity IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008565 protein transporter activity IDA
 molecular_functionGO:0015026 coreceptor activity IEA
 molecular_functionGO:0097643 amylin receptor activity IGI


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000064989 CALCRL / Q16602 / calcitonin receptor like receptor  / complex
 ENSG00000004948 CALCR / P30988 / calcitonin receptor  / complex
 ENSG00000121351 IAPP / P10997 / islet amyloid polypeptide  / complex / reaction
 ENSG00000148926 ADM / P35318 / adrenomedullin  / complex / reaction
 ENSG00000128165 ADM2 / Q7Z4H4 / adrenomedullin 2  / complex / reaction






 

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