ENSG00000132329


Homo sapiens

Features
Gene ID: ENSG00000132329
  
Biological name :RAMP1
  
Synonyms : O60894 / RAMP1 / receptor activity modifying protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.3
Gene start: 237858893
Gene end: 237912114
  
Corresponding Affymetrix probe sets: 204916_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386720
Ensembl peptide - ENSP00000254661
Ensembl peptide - ENSP00000384688
Ensembl peptide - ENSP00000386046
NCBI entrez gene - 10267     See in Manteia.
OMIM - 605153
RefSeq - XM_017003156
RefSeq - NM_001308353
RefSeq - NM_005855
RefSeq - XM_017003152
RefSeq - XM_017003153
RefSeq - XM_017003154
RefSeq Peptide - NP_001295282
RefSeq Peptide - NP_005846
swissprot - E9PC20
swissprot - O60894
Ensembl - ENSG00000132329
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:91818ENSDARG00000056704Danio rerio
 RAMP1ENSGALG00000003821Gallus gallus
 Ramp1ENSMUSG00000034353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAMP3 / O60896 / receptor activity modifying protein 3ENSG0000012267930
RAMP2 / O60895 / receptor activity modifying protein 2ENSG0000013147728


Protein motifs (from Interpro)
Interpro ID Name
 IPR006985  Receptor activity modifying protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IPI
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0015031 protein transport IDA
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process IGI
 biological_processGO:0031623 receptor internalization IDA
 biological_processGO:0060050 positive regulation of protein glycosylation IDA
 biological_processGO:0072659 protein localization to plasma membrane IDA
 biological_processGO:0097647 amylin receptor signaling pathway IGI
 biological_processGO:1990408 calcitonin gene-related peptide receptor signaling pathway IPI
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:1903440 amylin receptor complex IDA
 cellular_componentGO:1990406 CGRP receptor complex IDA
 molecular_functionGO:0001635 calcitonin gene-related peptide receptor activity IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:0015026 coreceptor activity IEA
 molecular_functionGO:0097643 amylin receptor activity IGI
 molecular_functionGO:1990407 calcitonin gene-related peptide binding IPI


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000121351 IAPP / P10997 / islet amyloid polypeptide  / complex / reaction
 ENSG00000004948 CALCR / P30988 / calcitonin receptor  / complex
 ENSG00000064989 CALCRL / Q16602 / calcitonin receptor like receptor  / complex
 ENSG00000175868 CALCB / P10092 / calcitonin related polypeptide beta  / reaction / complex
 ENSG00000110680 CALCA / P01258 / P06881 / calcitonin related polypeptide alpha  / reaction / complex






 

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