ENSG00000175868


Homo sapiens

Features
Gene ID: ENSG00000175868
  
Biological name :CALCB
  
Synonyms : CALCB / calcitonin related polypeptide beta / P10092
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.2
Gene start: 14904997
Gene end: 15082342
  
Corresponding Affymetrix probe sets: 214636_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428882
Ensembl peptide - ENSP00000433490
Ensembl peptide - ENSP00000346017
NCBI entrez gene - 797     See in Manteia.
OMIM - 114160
RefSeq - NM_000728
RefSeq Peptide - NP_000719
swissprot - E7ESF5
swissprot - P10092
Ensembl - ENSG00000175868
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 calcaENSDARG00000056590Danio rerio
 CalcbENSMUSG00000030666Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CALCA / P01258 / P06881 / calcitonin related polypeptide alphaENSG0000011068058


Protein motifs (from Interpro)
Interpro ID Name
 IPR001693  Calcitonin peptide-like
 IPR015476  Calcitonin gene-related peptide
 IPR018360  Calcitonin, conserved site
 IPR021116  Calcitonin/adrenomedullin
 IPR021117  Calcitonin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006874 cellular calcium ion homeostasis TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity TAS


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000064989 CALCRL / Q16602 / calcitonin receptor like receptor  / complex / reaction
 ENSG00000132329 RAMP1 / O60894 / receptor activity modifying protein 1  / reaction / complex






 

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