ENSMUSG00000041046


Mus musculus

Features
Gene ID: ENSMUSG00000041046
  
Biological name :Ramp3
  
Synonyms : Q9WUP1 / Ramp3 / Receptor activity-modifying protein 3
  
Possible biological names infered from orthology : O60896
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: A1
Gene start: 6658521
Gene end: 6677475
  
Corresponding Affymetrix probe sets: 10374197 (MoGene1.0st)   1420401_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047518
NCBI entrez gene - 56089     See in Manteia.
MGI - MGI:1860292
RefSeq - NM_019511
RefSeq - XM_006514761
RefSeq Peptide - NP_062384
swissprot - Q9WUP1
Ensembl - ENSMUSG00000041046
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAMP3ENSGALG00000037246Gallus gallus
 RAMP3ENSG00000122679Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ramp1 / Q9WTJ5 / receptor (calcitonin) activity modifying protein 1 / O60894* / receptor activity modifying protein 1*ENSMUSG0000003435331
Ramp2 / Q9WUP0 / Receptor activity-modifying protein 2 / O60895*ENSMUSG0000000124029


Protein motifs (from Interpro)
Interpro ID Name
 IPR006985  Receptor activity modifying protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001921 positive regulation of receptor recycling IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IPI
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010739 positive regulation of protein kinase A signaling IEA
 biological_processGO:0010942 positive regulation of cell death IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IDA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0086103 G-protein coupled receptor signaling pathway involved in heart process IMP
 biological_processGO:0097647 amylin receptor signaling pathway IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 biological_processGO:1905665 positive regulation of calcium ion import across plasma membrane IEA
 biological_processGO:1990410 adrenomedullin receptor signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:1903143 adrenomedullin receptor complex IEA
 cellular_componentGO:1903440 amylin receptor complex IEA
 molecular_functionGO:0001605 adrenomedullin receptor activity IEA
 molecular_functionGO:0008565 protein transporter activity ISO
 molecular_functionGO:0015026 coreceptor activity IEA
 molecular_functionGO:0097643 amylin receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Adgrv1tm2Msat/Adgrv1tm2Msat
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030790 Adm / P97297 / ADM Adrenomedullin Proadrenomedullin N-20 terminal peptide / P35318* / adrenomedullin*  / reaction / complex
 ENSMUSG00000054136 Adm2 / Q7TNK8 / ADM2 Adrenomedullin-2 Intermedin-short / Q7Z4H4* / adrenomedullin 2*  / complex / reaction
 ENSMUSG00000041681 Iapp / P12968 / Islet amyloid polypeptide / P10997*  / reaction / complex
 ENSMUSG00000023964 Calcr / Q60755 / Mus musculus calcitonin receptor (Calcr), transcript variant 3, mRNA. / P30988* / calcitonin receptor*  / complex
 ENSMUSG00000059588 Calcrl / Q9R1W5 / Calcitonin-related peptide type 1 receptor / Q16602* / calcitonin receptor like receptor*  / complex






 

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