ENSG00000128309


Homo sapiens

Features
Gene ID: ENSG00000128309
  
Biological name :MPST
  
Synonyms : mercaptopyruvate sulfurtransferase / MPST / P25325
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q12.3
Gene start: 37019635
Gene end: 37029822
  
Corresponding Affymetrix probe sets: 203524_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384812
Ensembl peptide - ENSP00000486251
Ensembl peptide - ENSP00000411719
Ensembl peptide - ENSP00000385062
Ensembl peptide - ENSP00000342333
Ensembl peptide - ENSP00000380402
Ensembl peptide - ENSP00000383950
NCBI entrez gene - 4357     See in Manteia.
OMIM - 602496
RefSeq - XM_005261610
RefSeq - XM_011530196
RefSeq - NM_001130517
RefSeq - NM_021126
RefSeq - XM_011530195
RefSeq - NM_001013436
RefSeq Peptide - NP_001013454
RefSeq Peptide - NP_001123989
RefSeq Peptide - NP_066949
swissprot - P25325
swissprot - B1AH49
swissprot - A0A140VJX3
Ensembl - ENSG00000128309
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TSTENSDARG00000093235Danio rerio
 MPSTENSGALG00000040840Gallus gallus
 MpstENSMUSG00000071711Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TST / Q16762 / thiosulfate sulfurtransferaseENSG0000012831156


Protein motifs (from Interpro)
Interpro ID Name
 IPR001307  Thiosulphate sulfurtransferase, conserved site
 IPR001763  Rhodanese-like domain
 IPR036873  Rhodanese-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0009440 cyanate catabolic process TAS
 biological_processGO:0009636 response to toxic substance TAS
 biological_processGO:0019346 transsulfuration IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0070814 hydrogen sulfide biosynthetic process ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004792 thiosulfate sulfurtransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016784 3-mercaptopyruvate sulfurtransferase activity ISS
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Degradation of cysteine and homocysteine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100348 TXN2 / Q99757 / thioredoxin 2  / reaction / complex






 

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contact: otassy@igbmc.fr