ENSMUSG00000071711


Mus musculus

Features
Gene ID: ENSMUSG00000071711
  
Biological name :Mpst
  
Synonyms : mercaptopyruvate sulfurtransferase / Mpst
  
Possible biological names infered from orthology : P25325
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 78406416
Gene end: 78414013
  
Corresponding Affymetrix probe sets: 10425078 (MoGene1.0st)   1418356_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043061
Ensembl peptide - ENSMUSP00000128075
Ensembl peptide - ENSMUSP00000130493
Ensembl peptide - ENSMUSP00000155371
Ensembl peptide - ENSMUSP00000155399
Ensembl peptide - ENSMUSP00000155018
NCBI entrez gene - 246221     See in Manteia.
MGI - MGI:2179733
RefSeq - XM_006520996
RefSeq - NM_001162492
RefSeq - NM_001162493
RefSeq - NM_138670
RefSeq - XM_006520994
RefSeq - XM_006520995
RefSeq Peptide - NP_001155964
RefSeq Peptide - NP_001155965
RefSeq Peptide - NP_619611
swissprot - Q3UW66
Ensembl - ENSMUSG00000071711
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TSTENSDARG00000093235Danio rerio
 MPSTENSGALG00000040840Gallus gallus
 MPSTENSG00000128309Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tst / P52196 / thiosulfate sulfurtransferase, mitochondrial / Q16762* / thiosulfate sulfurtransferase*ENSMUSG0000004498658


Protein motifs (from Interpro)
Interpro ID Name
 IPR001307  Thiosulphate sulfurtransferase, conserved site
 IPR001763  Rhodanese-like domain
 IPR036873  Rhodanese-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0004792 thiosulfate sulfurtransferase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of cysteine and homocysteine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001152 Leydig cell hyperplasia "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065]
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Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
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Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

 MP:0001940 testicular hypoplasia "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

 MP:0010069 increased serotonin concentration "increase in the amount per unit of biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets that mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Eml1heco/Eml1heco
Genetic Background: involves: C57BL/6 * NOR

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005354 Txn2 / P97493 / thioredoxin 2 / Q99757*  / complex / reaction






 

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