ENSG00000128708


Homo sapiens

Features
Gene ID: ENSG00000128708
  
Biological name :HAT1
  
Synonyms : HAT1 / histone acetyltransferase 1 / O14929
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q31.1
Gene start: 171922448
Gene end: 171983682
  
Corresponding Affymetrix probe sets: 203138_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264108
Ensembl peptide - ENSP00000403466
Ensembl peptide - ENSP00000407921
NCBI entrez gene - 8520     See in Manteia.
OMIM - 603053
RefSeq - XM_017005137
RefSeq - NM_003642
RefSeq - XM_006712808
RefSeq - XM_011512027
RefSeq - XM_017005136
RefSeq Peptide - NP_003633
swissprot - F8WEW1
swissprot - F8W9G7
swissprot - O14929
Ensembl - ENSG00000128708
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hat1ENSDARG00000034916Danio rerio
 HAT1ENSGALG00000009525Gallus gallus
 Hat1ENSMUSG00000027018Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016181  Acyl-CoA N-acyltransferase
 IPR017380  Histone acetyltransferase type B, catalytic subunit
 IPR019467  Histone acetyl transferase HAT1 N-terminal
 IPR037113  Histone acetyl transferase 1, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006323 DNA packaging TAS
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006335 DNA replication-dependent nucleosome assembly IDA
 biological_processGO:0006336 DNA replication-independent nucleosome assembly IDA
 biological_processGO:0006348 chromatin silencing at telomere IEA
 biological_processGO:0006475 internal protein amino acid acetylation TAS
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0043967 histone H4 acetylation IDA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region HDA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004402 histone acetyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0010485 H4 histone acetyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0042393 histone binding IBA


Pathways (from Reactome)
Pathway description
HATs acetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / reaction
 ENSG00000102054 RBBP7 / Q16576 / RB binding protein 7, chromatin remodeling factor  / complex






 

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contact: otassy@igbmc.fr