ENSG00000129219


Homo sapiens

Features
Gene ID: ENSG00000129219
  
Biological name :PLD2
  
Synonyms : O14939 / phospholipase D2 / PLD2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.2
Gene start: 4807096
Gene end: 4823434
  
Corresponding Affymetrix probe sets: 209643_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461459
Ensembl peptide - ENSP00000460250
Ensembl peptide - ENSP00000460477
Ensembl peptide - ENSP00000263088
Ensembl peptide - ENSP00000458795
Ensembl peptide - ENSP00000459304
Ensembl peptide - ENSP00000459571
NCBI entrez gene - 5338     See in Manteia.
OMIM - 602384
RefSeq - XM_017024764
RefSeq - NM_001243108
RefSeq - NM_002663
RefSeq - XM_005256696
RefSeq Peptide - NP_002654
RefSeq Peptide - NP_001230037
swissprot - I3L1F3
swissprot - I3L222
swissprot - I3L381
swissprot - I3L4R5
swissprot - I3L3I7
swissprot - O14939
Ensembl - ENSG00000129219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pld2ENSDARG00000034262Danio rerio
 Pld2ENSMUSG00000020828Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLD1 / Q13393 / phospholipase D1ENSG0000007565156


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR001736  Phospholipase D/Transphosphatidylase
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015679  Phospholipase D family
 IPR016555  Phospholipase D, eukaryotic type
 IPR025202  Phospholipase D-like domain
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006654 phosphatidic acid biosynthetic process TAS
 biological_processGO:0007010 cytoskeleton organization TAS
 biological_processGO:0007264 small GTPase mediated signal transduction TAS
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0036465 synaptic vesicle recycling TAS
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0048017 inositol lipid-mediated signaling IEA
 biological_processGO:0048870 cell motility IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004630 phospholipase D activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PG
Synthesis of PA
Role of phospholipids in phagocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr