ENSG00000130772


Homo sapiens

Features
Gene ID: ENSG00000130772
  
Biological name :MED18
  
Synonyms : MED18 / mediator complex subunit 18 / Q9BUE0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.3
Gene start: 28329002
Gene end: 28335967
  
Corresponding Affymetrix probe sets: 219730_at (Human Genome U133 Plus 2.0 Array)   221650_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362948
Ensembl peptide - ENSP00000381963
NCBI entrez gene - 54797     See in Manteia.
OMIM - 612384
RefSeq - XM_005245914
RefSeq - NM_001127350
RefSeq - NM_017638
RefSeq Peptide - NP_060108
RefSeq Peptide - NP_001120822
swissprot - Q9BUE0
Ensembl - ENSG00000130772
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med18ENSDARG00000041237Danio rerio
 MED18ENSGALG00000028149Gallus gallus
 Med18ENSMUSG00000066042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019095  Mediator complex, subunit Med18


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006369 termination of RNA polymerase II transcription IBA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016592 mediator complex IDA
 cellular_componentGO:0070847 core mediator complex IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr