ENSMUSG00000066042


Mus musculus

Features
Gene ID: ENSMUSG00000066042
  
Biological name :Med18
  
Synonyms : Med18 / Mediator of RNA polymerase II transcription subunit 18 / Q9CZ82
  
Possible biological names infered from orthology : mediator complex subunit 18 / Q9BUE0
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.3
Gene start: 132458731
Gene end: 132463921
  
Corresponding Affymetrix probe sets: 10516926 (MoGene1.0st)   1460462_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120535
Ensembl peptide - ENSMUSP00000099627
NCBI entrez gene - 67219     See in Manteia.
MGI - MGI:1914469
RefSeq - NM_026039
RefSeq Peptide - NP_080315
swissprot - A8Y5Q6
swissprot - Q9CZ82
Ensembl - ENSMUSG00000066042
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med18ENSDARG00000041237Danio rerio
 MED18ENSGALG00000028149Gallus gallus
 MED18ENSG00000130772Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019095  Mediator complex, subunit Med18


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006369 termination of RNA polymerase II transcription IBA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016592 mediator complex IEA
 cellular_componentGO:0070847 core mediator complex IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

 MP:0003062 abnormal coping response "altered ability to respond productively to a stressful situation or stimulus, or failure to seek pleasurable stimuli" [RGD:Rat Genome Database submission]
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Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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