ENSG00000130957


Homo sapiens

Features
Gene ID: ENSG00000130957
  
Biological name :FBP2
  
Synonyms : FBP2 / fructose-bisphosphatase 2 / O00757
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q22.32
Gene start: 94558720
Gene end: 94593793
  
Corresponding Affymetrix probe sets: 206844_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364486
NCBI entrez gene - 8789     See in Manteia.
OMIM - 603027
RefSeq - NM_003837
RefSeq Peptide - NP_003828
swissprot - O00757
Ensembl - ENSG00000130957
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbp2ENSDARG00000012366Danio rerio
 FBP2ENSGALG00000012612Gallus gallus
 Fbp2ENSMUSG00000021456Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBP1 / P09467 / fructose-bisphosphatase 1ENSG0000016514076


Protein motifs (from Interpro)
Interpro ID Name
 IPR000146  Fructose-1,6-bisphosphatase class 1
 IPR020548  Fructose-1,6-bisphosphatase, active site
 IPR028343  Fructose-1,6-bisphosphatase
 IPR033391  Fructose-1-6-bisphosphatase class I, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005986 sucrose biosynthetic process IBA
 biological_processGO:0006000 fructose metabolic process TAS
 biological_processGO:0006002 fructose 6-phosphate metabolic process IBA
 biological_processGO:0006094 gluconeogenesis TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030388 fructose 1,6-bisphosphate metabolic process IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity TAS
 molecular_functionGO:0042578 phosphoric ester hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000130957 FBP2 / O00757 / fructose-bisphosphatase 2  / complex






 

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