ENSG00000131142


Homo sapiens

Features
Gene ID: ENSG00000131142
  
Biological name :CCL25
  
Synonyms : CCL25 / C-C motif chemokine ligand 25 / O15444
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.2
Gene start: 8052767
Gene end: 8062650
  
Corresponding Affymetrix probe sets: 206988_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401882
Ensembl peptide - ENSP00000253451
Ensembl peptide - ENSP00000324756
Ensembl peptide - ENSP00000375086
NCBI entrez gene - 6370     See in Manteia.
OMIM - 602565
RefSeq - XM_017027122
RefSeq - NM_005624
RefSeq - XM_011528177
RefSeq - XM_017027119
RefSeq - XM_017027120
RefSeq - XM_017027121
RefSeq - NM_001201359
RefSeq Peptide - NP_001188288
RefSeq Peptide - NP_005615
swissprot - F8VWI0
swissprot - O15444
swissprot - C9JDZ7
Ensembl - ENSG00000131142
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ccl25ENSMUSG00000023235Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001811  Chemokine interleukin-8-like domain
 IPR034133  Chemokine CC, DCCL motif-cointaining domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IDA
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:1903237 negative regulation of leukocyte tethering or rolling IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005179 hormone activity TAS
 molecular_functionGO:0008009 chemokine activity IEA
 molecular_functionGO:0031735 CCR10 chemokine receptor binding IDA
 molecular_functionGO:0042379 chemokine receptor binding IDA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129048 ACKR4 / Q9NPB9 / atypical chemokine receptor 4  / reaction / complex
 ENSG00000173585 CCR9 / P51686 / C-C motif chemokine receptor 9  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr