ENSG00000131153


Homo sapiens

Features
Gene ID: ENSG00000131153
  
Biological name :GINS2
  
Synonyms : GINS2 / GINS complex subunit 2 / Q9Y248
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q24.1
Gene start: 85676198
Gene end: 85690073
  
Corresponding Affymetrix probe sets: 1557595_at (Human Genome U133 Plus 2.0 Array)   221521_s_at (Human Genome U133 Plus 2.0 Array)   243136_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000469346
Ensembl peptide - ENSP00000470984
Ensembl peptide - ENSP00000253462
NCBI entrez gene - 51659     See in Manteia.
OMIM - 610609
RefSeq - NM_016095
RefSeq Peptide - NP_057179
swissprot - Q9Y248
swissprot - M0QXS3
swissprot - M0R043
Ensembl - ENSG00000131153
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gins2ENSDARG00000002304Danio rerio
 GINS2ENSGALG00000033063Gallus gallus
 Gins2ENSMUSG00000031821Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007257  DNA replication complex GINS protein Psf2
 IPR021151  GINS subunit, domain A
 IPR036224  GINS, helical bundle-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000727 double-strand break repair via break-induced replication IBA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006271 DNA strand elongation involved in DNA replication TAS
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:1902975 mitotic DNA replication initiation IBA
 cellular_componentGO:0000811 GINS complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0031298 replication fork protection complex IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043138 3"-5" DNA helicase activity IBA


Pathways (from Reactome)
Pathway description
Unwinding of DNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101003 GINS1 / Q14691 / GINS complex subunit 1  / reaction / complex
 ENSG00000093009 CDC45 / O75419 / cell division cycle 45  / reaction / complex
 ENSG00000147536 GINS4 / Q9BRT9 / GINS complex subunit 4  / complex / reaction
 ENSG00000181938 GINS3 / Q9BRX5 / GINS complex subunit 3  / reaction / complex






 

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