ENSG00000101003


Homo sapiens

Features
Gene ID: ENSG00000101003
  
Biological name :GINS1
  
Synonyms : GINS1 / GINS complex subunit 1 / Q14691
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p11.21
Gene start: 25407727
Gene end: 25452628
  
Corresponding Affymetrix probe sets: 206102_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262460
NCBI entrez gene - 9837     See in Manteia.
OMIM - 610608
RefSeq - NM_021067
RefSeq - XM_017028162
RefSeq Peptide - NP_066545
swissprot - Q14691
Ensembl - ENSG00000101003
  
Related genetic diseases (OMIM): 617827 - Immunodeficiency 55, 617827
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gins1ENSDARG00000007624Danio rerio
 GINS1ENSGALG00000008538Gallus gallus
 Gins1ENSMUSG00000027454Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005339  GINS complex, subunit Psf1
 IPR036224  GINS, helical bundle-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001833 inner cell mass cell proliferation IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006271 DNA strand elongation involved in DNA replication TAS
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:1902983 DNA strand elongation involved in mitotic DNA replication IBA
 cellular_componentGO:0000811 GINS complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0043138 3"-5" DNA helicase activity IBA


Pathways (from Reactome)
Pathway description
Unwinding of DNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131153 GINS2 / Q9Y248 / GINS complex subunit 2  / reaction / complex
 ENSG00000093009 CDC45 / O75419 / cell division cycle 45  / reaction / complex
 ENSG00000147536 GINS4 / Q9BRT9 / GINS complex subunit 4  / complex / reaction
 ENSG00000181938 GINS3 / Q9BRX5 / GINS complex subunit 3  / complex / reaction






 

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