ENSG00000147536


Homo sapiens

Features
Gene ID: ENSG00000147536
  
Biological name :GINS4
  
Synonyms : GINS4 / GINS complex subunit 4 / Q9BRT9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p11.21
Gene start: 41529206
Gene end: 41545046
  
Corresponding Affymetrix probe sets: 1554356_at (Human Genome U133 Plus 2.0 Array)   211767_at (Human Genome U133 Plus 2.0 Array)   235029_at (Human Genome U133 Plus 2.0 Array)   240778_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428901
Ensembl peptide - ENSP00000429894
Ensembl peptide - ENSP00000429581
Ensembl peptide - ENSP00000276533
Ensembl peptide - ENSP00000428754
NCBI entrez gene - 84296     See in Manteia.
OMIM - 610611
RefSeq - NM_032336
RefSeq - XM_005273659
RefSeq Peptide - NP_115712
swissprot - E5RH56
swissprot - E5RFF9
swissprot - Q9BRT9
Ensembl - ENSG00000147536
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gins4ENSDARG00000016044Danio rerio
 GINS4ENSGALG00000045374Gallus gallus
 Gins4ENSMUSG00000031546Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008591  GINS complex subunit Sld5
 IPR021151  GINS subunit, domain A
 IPR031633  DNA replication complex GINS protein SLD5, C-terminal
 IPR036224  GINS, helical bundle-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000727 double-strand break repair via break-induced replication IBA
 biological_processGO:0001833 inner cell mass cell proliferation IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006261 DNA-dependent DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IBA
 biological_processGO:0006271 DNA strand elongation involved in DNA replication TAS
 biological_processGO:0032508 DNA duplex unwinding IEA
 cellular_componentGO:0000811 GINS complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031298 replication fork protection complex IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043138 3"-5" DNA helicase activity IBA


Pathways (from Reactome)
Pathway description
Unwinding of DNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000093009 CDC45 / O75419 / cell division cycle 45  / reaction / complex
 ENSG00000101003 GINS1 / Q14691 / GINS complex subunit 1  / complex / reaction
 ENSG00000181938 GINS3 / Q9BRX5 / GINS complex subunit 3  / complex / reaction
 ENSG00000131153 GINS2 / Q9Y248 / GINS complex subunit 2  / complex / reaction






 

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