ENSG00000131381


Homo sapiens

Features
Gene ID: ENSG00000131381
  
Biological name :RBSN
  
Synonyms : Q9H1K0 / rabenosyn, RAB effector / RBSN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p25.1
Gene start: 15070073
Gene end: 15099163
  
Corresponding Affymetrix probe sets: 1569714_at (Human Genome U133 Plus 2.0 Array)   226581_at (Human Genome U133 Plus 2.0 Array)   231765_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000403368
Ensembl peptide - ENSP00000387724
Ensembl peptide - ENSP00000414020
Ensembl peptide - ENSP00000427038
Ensembl peptide - ENSP00000422551
Ensembl peptide - ENSP00000253699
NCBI entrez gene - 64145     See in Manteia.
OMIM - 609511
RefSeq - XM_017007028
RefSeq - XM_005265384
RefSeq - XM_005265385
RefSeq - XM_011534001
RefSeq - XM_017007023
RefSeq - XM_017007024
RefSeq - XM_017007025
RefSeq - XM_017007026
RefSeq - XM_017007027
RefSeq - NM_001302378
RefSeq - NM_022340
RefSeq Peptide - NP_001289307
RefSeq Peptide - NP_071735
swissprot - F8WE50
swissprot - H7C204
swissprot - D6RD50
swissprot - A0A024R2H4
swissprot - Q9H1K0
swissprot - C9JZZ1
Ensembl - ENSG00000131381
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rbsnENSDARG00000078215Danio rerio
 RBSNENSGALG00000008500Gallus gallus
 RbsnENSMUSG00000014550Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR017455  Zinc finger, FYVE-related
 IPR021565  Rabenosyn, Rab binding domain
 IPR036531  Rabenosyn, Rab binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000011 vacuole inheritance IBA
 biological_processGO:0006895 Golgi to endosome transport IBA
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport NAS
 biological_processGO:0034058 endosomal vesicle fusion IBA
 biological_processGO:0034498 early endosome to Golgi transport IMP
 biological_processGO:0090160 Golgi to lysosome transport IMP
 biological_processGO:1903358 regulation of Golgi organization IMP
 cellular_componentGO:0005768 endosome NAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0010009 cytoplasmic side of endosome membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 9 (TLR9) Cascade
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136631 VPS45 / Q9NRW7 / vacuolar protein sorting 45 homolog  / complex / reaction
 ENSG00000144566 RAB5A / P20339 / RAB5A, member RAS oncogene family  / complex / reaction
 ENSG00000024422 EHD2 / Q9NZN4 / EH domain containing 2  / reaction / complex
 ENSG00000013016 EHD3 / Q9NZN3 / EH domain containing 3  / complex / reaction
 ENSG00000110047 EHD1 / Q9H4M9 / EH domain containing 1  / complex / reaction






 

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