Manteia

ENSMUSG00000014550

Mus musculus

Features

Gene ID:	ENSMUSG00000014550

Biological name :	Rbsn

Synonyms :	Q80Y56 / Rabenosyn-5 / Rbsn

Possible biological names infered from orthology :	Q9H1K0 / rabenosyn, RAB effector

Species:	Mus musculus

Chr. number:	6
Strand:	-1
Band:	D1
Gene start:	92186712
Gene end:	92214925

Corresponding Affymetrix probe sets:	10546402 (MoGene1.0st) 1429517_at (Mouse Genome 430 2.0 Array) 1435093_at (Mouse Genome 430 2.0 Array) 1456754_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000014694 Ensembl peptide - ENSMUSP00000144945 Ensembl peptide - ENSMUSP00000144749 Ensembl peptide - ENSMUSP00000120883 NCBI entrez gene - 78287 See in Manteia. MGI - MGI:1925537 RefSeq - XM_006506769 RefSeq - NM_030081 RefSeq - XM_006506768 RefSeq Peptide - NP_084357 swissprot - D3Z0E7 swissprot - Q80Y56 swissprot - A0A0N4SUN4 swissprot - A0A0N4SV43 Ensembl - ENSMUSG00000014550

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR000306	FYVE zinc finger
IPR011011	Zinc finger, FYVE/PHD-type
IPR013083	Zinc finger, RING/FYVE/PHD-type
IPR013087	Zinc finger C2H2-type
IPR017455	Zinc finger, FYVE-related
IPR021565	Rabenosyn, Rab binding domain
IPR036531	Rabenosyn, Rab binding domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000011	vacuole inheritance	IBA
biological_process	GO:0006895	Golgi to endosome transport	IBA
biological_process	GO:0006896	Golgi to vacuole transport	IBA
biological_process	GO:0006897	endocytosis	IBA
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0034058	endosomal vesicle fusion	IBA
biological_process	GO:0034498	early endosome to Golgi transport	IEA
biological_process	GO:0090160	Golgi to lysosome transport	IEA
biological_process	GO:1903358	regulation of Golgi organization	IEA
cellular_component	GO:0005768	endosome	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0010009	cytoplasmic side of endosome membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031901	early endosome membrane	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
molecular_function	GO:0003676	nucleic acid binding	IEA
molecular_function	GO:0017137	Rab GTPase binding	IPI
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Toll Like Receptor 9 (TLR9) Cascade

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001325	abnormal retina morphology	"structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Psph^{tm1a(EUCOMM)Hmgu}/Psph⁺ Genetic Background: C57BL/6N-Psph^{tm1a(EUCOMM)Hmgu}/Wtsi
MP:0005103	abnormal retinal pigmentation	"anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Psph^{tm1a(EUCOMM)Hmgu}/Psph⁺ Genetic Background: C57BL/6N-Psph^{tm1a(EUCOMM)Hmgu}/Wtsi
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Rad21l^{tm1b(KOMP)Wtsi}/Rad21l^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Rad21l^{tm1b(KOMP)Wtsi}/J

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000015747	Vps45 / P97390 / vacuolar protein sorting 45 / Q9NRW7* / vacuolar protein sorting 45 homolog*	/ reaction / complex
ENSMUSG00000017831	Rab5a / Q9CQD1 / Ras-related protein Rab-5A / P20339* / RAB5A, member RAS oncogene family*	/ reaction / complex
ENSMUSG00000024772	Ehd1 / Q9WVK4 / EH domain-containing protein 1 / Q9H4M9* / EH domain containing 1*	/ complex / reaction
ENSMUSG00000024065	Ehd3 / Q9QXY6 / EH domain-containing protein 3 / Q9NZN3* / EH domain containing 3*	/ reaction / complex
ENSMUSG00000074364	Ehd2 / Q8BH64 / EH domain-containing protein 2 / Q9NZN4* / EH domain containing 2*	/ complex / reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr