ENSG00000131748


Homo sapiens

Features
Gene ID: ENSG00000131748
  
Biological name :STARD3
  
Synonyms : Q14849 / STARD3 / StAR related lipid transfer domain containing 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 39637065
Gene end: 39663484
  
Corresponding Affymetrix probe sets: 202991_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464288
Ensembl peptide - ENSP00000464204
Ensembl peptide - ENSP00000464472
Ensembl peptide - ENSP00000337446
Ensembl peptide - ENSP00000377794
Ensembl peptide - ENSP00000411710
Ensembl peptide - ENSP00000439869
Ensembl peptide - ENSP00000462483
Ensembl peptide - ENSP00000462541
Ensembl peptide - ENSP00000462859
Ensembl peptide - ENSP00000463460
Ensembl peptide - ENSP00000463613
Ensembl peptide - ENSP00000463681
NCBI entrez gene - 10948     See in Manteia.
OMIM - 607048
RefSeq - XM_017024041
RefSeq - NM_001165937
RefSeq - NM_001165938
RefSeq - NM_006804
RefSeq - XM_006721646
RefSeq - XM_011524210
RefSeq - XM_011524211
RefSeq - XM_011524213
RefSeq Peptide - NP_001159409
RefSeq Peptide - NP_001159410
RefSeq Peptide - NP_006795
swissprot - C9J555
swissprot - J3KSH0
swissprot - J3KSL3
swissprot - J3KT87
swissprot - J3QLA7
swissprot - J3QLM1
swissprot - J3QLS1
swissprot - J3QRM3
swissprot - J3QRG8
swissprot - J3QS10
swissprot - Q14849
Ensembl - ENSG00000131748
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9DFS4ENSDARG00000017809Danio rerio
 STARD3ENSGALG00000014607Gallus gallus
 Q61542ENSMUSG00000018167Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O95772 / STARD3NL / STARD3 N-terminal likeENSG0000001027029
STAR / P49675 / steroidogenic acute regulatory proteinENSG0000014746520


Protein motifs (from Interpro)
Interpro ID Name
 IPR000799  Steroidogenic acute regulatory protein-like
 IPR002913  START domain
 IPR019498  MENTAL domain
 IPR023393  START-like domain superfamily
 IPR029867  StAR-related lipid transfer protein 3, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process TAS
 biological_processGO:0006700 C21-steroid hormone biosynthetic process TAS
 biological_processGO:0006701 progesterone biosynthetic process IEA
 biological_processGO:0006839 mitochondrial transport TAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0008202 steroid metabolic process TAS
 biological_processGO:0008203 cholesterol metabolic process TAS
 biological_processGO:0030301 cholesterol transport IDA
 biological_processGO:0099044 vesicle tethering to endoplasmic reticulum IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0044232 organelle membrane contact site IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0017127 cholesterol transporter activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Pregnenolone biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000147465 STAR / P49675 / steroidogenic acute regulatory protein  / reaction
 ENSG00000010270 O95772 / STARD3NL / STARD3 N-terminal like  / complex






 

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