ENSG00000132254


Homo sapiens

Features
Gene ID: ENSG00000132254
  
Biological name :ARFIP2
  
Synonyms : ADP ribosylation factor interacting protein 2 / ARFIP2 / P53365
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.4
Gene start: 6474683
Gene end: 6481479
  
Corresponding Affymetrix probe sets: 202109_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391427
Ensembl peptide - ENSP00000484121
Ensembl peptide - ENSP00000434564
Ensembl peptide - ENSP00000434124
Ensembl peptide - ENSP00000398375
Ensembl peptide - ENSP00000254584
Ensembl peptide - ENSP00000379998
NCBI entrez gene - 23647     See in Manteia.
OMIM - 601638
RefSeq - XM_005252840
RefSeq - NM_001242854
RefSeq - NM_001242855
RefSeq - NM_001242856
RefSeq - NM_012402
RefSeq Peptide - NP_001229783
RefSeq Peptide - NP_001229784
RefSeq Peptide - NP_001229785
RefSeq Peptide - NP_036534
swissprot - A0A087X1E4
swissprot - E9PRV8
swissprot - P53365
swissprot - E9PPY7
Ensembl - ENSG00000132254
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arfip2aENSDARG00000059244Danio rerio
 arfip2bENSDARG00000056664Danio rerio
 ARFIP2ENSGALG00000037839Gallus gallus
 Arfip2ENSMUSG00000030881Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARFIP1 / P53367 / ADP ribosylation factor interacting protein 1ENSG0000016414454


Protein motifs (from Interpro)
Interpro ID Name
 IPR010504  Arfaptin homology (AH) domain
 IPR027267  AH/BAR domain superfamily
 IPR030798  Arfaptin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction TAS
 biological_processGO:0030032 lamellipodium assembly TAS
 biological_processGO:0030036 actin cytoskeleton organization IMP
 biological_processGO:0031529 ruffle organization TAS
 biological_processGO:0034315 regulation of Arp2/3 complex-mediated actin nucleation IBA
 cellular_componentGO:0001726 ruffle IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0032588 trans-Golgi network membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding TAS
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0048365 Rac GTPase binding TAS
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IDA


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000120805 ARL1 / P40616 / ADP ribosylation factor like GTPase 1  / complex / reaction






 

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