ENSG00000120805


Homo sapiens

Features
Gene ID: ENSG00000120805
  
Biological name :ARL1
  
Synonyms : ADP ribosylation factor like GTPase 1 / ARL1 / P40616
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q23.2
Gene start: 101393120
Gene end: 101407820
  
Corresponding Affymetrix probe sets: 201657_at (Human Genome U133 Plus 2.0 Array)   201658_at (Human Genome U133 Plus 2.0 Array)   201659_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448912
Ensembl peptide - ENSP00000450315
Ensembl peptide - ENSP00000450162
Ensembl peptide - ENSP00000261636
Ensembl peptide - ENSP00000439590
Ensembl peptide - ENSP00000441808
Ensembl peptide - ENSP00000447405
Ensembl peptide - ENSP00000448850
NCBI entrez gene - 400     See in Manteia.
OMIM - 603425
RefSeq - NM_001177
RefSeq - NM_001301068
RefSeq Peptide - NP_001168
RefSeq Peptide - NP_001287997
swissprot - B4DZG7
swissprot - P40616
swissprot - F8VP63
swissprot - F8VP99
swissprot - F8VYN9
swissprot - F8W1Z8
Ensembl - ENSG00000120805
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arl1ENSDARG00000101680Danio rerio
 ARL1ENSGALG00000011651Gallus gallus
 Arl1ENSMUSG00000060904Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARL5B / Q96KC2 / ADP ribosylation factor like GTPase 5BENSG0000016599749
ARL5A / Q9Y689 / ADP ribosylation factor like GTPase 5AENSG0000016298049
ARL6 / Q9H0F7 / ADP ribosylation factor like GTPase 6ENSG0000011396639
ARL5C / A6NH57 / ADP ribosylation factor like GTPase 5CENSG0000014174839


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007030 Golgi organization ISS
 biological_processGO:0009404 toxin metabolic process IDA
 biological_processGO:0031584 activation of phospholipase D activity IDA
 biological_processGO:0034067 protein localization to Golgi apparatus IMP
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:0048193 Golgi vesicle transport IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IDA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008047 enzyme activator activity IDA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132254 ARFIP2 / P53365 / ADP ribosylation factor interacting protein 2  / complex / reaction
 ENSG00000204070 SYS1 / Q8N2H4 / SYS1, golgi trafficking protein  / reaction / complex
 ENSG00000153130 SCOC / Q9UIL1 / short coiled-coil protein  / complex / reaction
 ENSG00000101246 ARFRP1 / Q13795 / ADP ribosylation factor related protein 1  / reaction / complex






 

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