ENSG00000132432


Homo sapiens

Features
Gene ID: ENSG00000132432
  
Biological name :SEC61G
  
Synonyms : P60059 / SEC61G / Sec61 translocon gamma subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p11.2
Gene start: 54752250
Gene end: 54759974
  
Corresponding Affymetrix probe sets: 203484_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378906
Ensembl peptide - ENSP00000409884
Ensembl peptide - ENSP00000388337
Ensembl peptide - ENSP00000341538
NCBI entrez gene - 23480     See in Manteia.
OMIM - 609215
RefSeq - NM_001012456
RefSeq - NM_014302
RefSeq Peptide - NP_001012474
RefSeq Peptide - NP_055117
swissprot - A0A024QYZ0
swissprot - P60059
Ensembl - ENSG00000132432
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sec61gENSDARG00000018637Danio rerio
 SEC61GENSGALG00000037863Gallus gallus
 P60060ENSMUSG00000078974Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001901  Protein translocase complex, SecE/Sec61-gamma subunit
 IPR008158  Protein translocase SEC61 complex, gamma subunit
 IPR022943  Preprotein translocase subunit SecE
 IPR023391  Protein translocase SecE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0045047 protein targeting to ER ISS
 biological_processGO:0071806 protein transmembrane transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008565 protein transporter activity ISS
 molecular_functionGO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
SRP-dependent cotranslational protein targeting to membrane
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106803 P60468 / SEC61B / Sec61 translocon beta subunit  / complex
 ENSG00000058262 P61619 / SEC61A1 / Sec61 translocon alpha 1 subunit  / complex
 ENSG00000065665 Q9H9S3 / SEC61A2 / Sec61 translocon alpha 2 subunit  / complex
 ENSG00000008952 SEC62 / Q99442 / SEC62 homolog, preprotein translocation factor  / complex
 ENSG00000025796 SEC63 / Q9UGP8 / SEC63 homolog, protein translocation regulator  / complex
 ENSG00000198356 ASNA1 / O43681 / arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)  / reaction






 

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