ENSG00000008952


Homo sapiens

Features
Gene ID: ENSG00000008952
  
Biological name :SEC62
  
Synonyms : Q99442 / SEC62 / SEC62 homolog, preprotein translocation factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q26.2
Gene start: 169966635
Gene end: 169998373
  
Corresponding Affymetrix probe sets: 1552789_at (Human Genome U133 Plus 2.0 Array)   1552790_a_at (Human Genome U133 Plus 2.0 Array)   208942_s_at (Human Genome U133 Plus 2.0 Array)   208943_s_at (Human Genome U133 Plus 2.0 Array)   225352_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418342
Ensembl peptide - ENSP00000420304
Ensembl peptide - ENSP00000420331
Ensembl peptide - ENSP00000337688
Ensembl peptide - ENSP00000419319
NCBI entrez gene - 7095     See in Manteia.
OMIM - 602173
RefSeq - XM_011513114
RefSeq - NM_003262
RefSeq Peptide - NP_003253
swissprot - F8WF48
swissprot - F8WCJ7
swissprot - Q99442
swissprot - F8WDG8
Ensembl - ENSG00000008952
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sec62ENSDARG00000019951Danio rerio
 SEC62ENSGALG00000009379Gallus gallus
 Sec62ENSMUSG00000027706Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004728  Translocation protein Sec62
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006613 cotranslational protein targeting to membrane TAS
 biological_processGO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005791 rough endoplasmic reticulum ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106803 P60468 / SEC61B / Sec61 translocon beta subunit  / complex
 ENSG00000058262 P61619 / SEC61A1 / Sec61 translocon alpha 1 subunit  / complex
 ENSG00000065665 Q9H9S3 / SEC61A2 / Sec61 translocon alpha 2 subunit  / complex
 ENSG00000132432 P60059 / SEC61G / Sec61 translocon gamma subunit  / complex
 ENSG00000198356 ASNA1 / O43681 / arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)  / reaction
 ENSG00000025796 SEC63 / Q9UGP8 / SEC63 homolog, protein translocation regulator  / complex






 

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