ENSG00000132688


Homo sapiens

Features
Gene ID: ENSG00000132688
  
Biological name :NES
  
Synonyms : NES / nestin / P48681
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.1
Gene start: 156668763
Gene end: 156677397
  
Corresponding Affymetrix probe sets: 218678_at (Human Genome U133 Plus 2.0 Array)   229346_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357206
NCBI entrez gene - 10763     See in Manteia.
OMIM - 600915
RefSeq - NM_006617
RefSeq Peptide - NP_006608
swissprot - P48681
Ensembl - ENSG00000132688
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NesENSMUSG00000004891Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYNM / O15061 / syneminENSG0000018225316


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR018039  Intermediate filament protein, conserved site
 IPR031211  Nestin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007417 central nervous system development NAS
 biological_processGO:0007420 brain development ISS
 biological_processGO:0030844 positive regulation of intermediate filament depolymerization ISS
 biological_processGO:0031076 embryonic camera-type eye development ISS
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0043086 negative regulation of catalytic activity IDA
 biological_processGO:0072089 stem cell proliferation IMP
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005882 intermediate filament NAS
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0019215 intermediate filament binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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