ENSG00000132970


Homo sapiens

Features
Gene ID: ENSG00000132970
  
Biological name :WASF3
  
Synonyms : Q9UPY6 / WASF3 / WAS protein family member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q12.13
Gene start: 26557703
Gene end: 26688948
  
Corresponding Affymetrix probe sets: 204042_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000335055
Ensembl peptide - ENSP00000354325
NCBI entrez gene - 10810     See in Manteia.
OMIM - 605068
RefSeq - XM_011534890
RefSeq - NM_001291965
RefSeq - NM_006646
RefSeq - XM_011534889
RefSeq Peptide - NP_001278894
RefSeq Peptide - NP_006637
swissprot - Q5T8P4
swissprot - Q9UPY6
Ensembl - ENSG00000132970
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wasf3aENSDARG00000059466Danio rerio
 wasf3bENSDARG00000062948Danio rerio
 WASF3ENSGALG00000017103Gallus gallus
 Wasf3ENSMUSG00000029636Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WASF1 / Q92558 / WAS protein family member 1ENSG0000011229050
WASF2 / Q9Y6W5 / WAS protein family member 2ENSG0000015819550


Protein motifs (from Interpro)
Interpro ID Name
 IPR003124  WH2 domain
 IPR028288  SCAR/WAVE family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0030032 lamellipodium assembly IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030041 actin filament polymerization TAS
 biological_processGO:0031643 positive regulation of myelination IEA
 biological_processGO:0065003 protein-containing complex assembly TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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