ENSG00000133138


Homo sapiens

Features
Gene ID: ENSG00000133138
  
Biological name :TBC1D8B
  
Synonyms : Q0IIM8 / TBC1D8B / TBC1 domain family member 8B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q22.3
Gene start: 106802680
Gene end: 106876145
  
Corresponding Affymetrix probe sets: 1563272_at (Human Genome U133 Plus 2.0 Array)   219771_at (Human Genome U133 Plus 2.0 Array)   238067_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000276175
Ensembl peptide - ENSP00000396440
Ensembl peptide - ENSP00000422353
Ensembl peptide - ENSP00000421375
Ensembl peptide - ENSP00000310675
Ensembl peptide - ENSP00000349781
NCBI entrez gene - 54885     See in Manteia.
RefSeq - XM_006724670
RefSeq - NM_017752
RefSeq - NM_198881
RefSeq - XM_006724669
RefSeq Peptide - NP_942582
RefSeq Peptide - NP_060222
swissprot - J3KN75
swissprot - Q0IIM8
swissprot - D6RFZ2
swissprot - H0Y552
swissprot - D6RC82
Ensembl - ENSG00000133138
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0R0W9ENSDARG00000062192Danio rerio
 TBC1D8BENSGALG00000009040Gallus gallus
 A3KGB4ENSMUSG00000042473Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ZT07 / TBC1D9 / TBC1 domain family member 9ENSG0000010943653
O95759 / TBC1D8 / TBC1 domain family member 8ENSG0000020463453
Q66K14 / TBC1D9B / TBC1 domain family member 9BENSG0000019722652
Q9BYX2 / TBC1D2 / TBC1 domain family member 2ENSG0000009538314
Q9UPU7 / TBC1D2B / TBC1 domain family member 2BENSG0000016720214
SGSM3 / Q96HU1 / small G protein signaling modulator 3ENSG0000010035913
Q9Y2I9 / TBC1D30 / TBC1 domain family member 30ENSG0000011149010


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR002048  EF-hand domain
 IPR004182  GRAM domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR035969  Rab-GTPase-TBC domain superfamily
 IPR036012  TBC1D8B, PH-GRAM domain 1
 IPR036015  TBC1D8B, PH-GRAM domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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