ENSG00000095383


Homo sapiens

Features
Gene ID: ENSG00000095383
  
Biological name :TBC1D2
  
Synonyms : Q9BYX2 / TBC1D2 / TBC1 domain family member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q22.33
Gene start: 98198999
Gene end: 98255721
  
Corresponding Affymetrix probe sets: 222173_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000341567
Ensembl peptide - ENSP00000364205
Ensembl peptide - ENSP00000364207
Ensembl peptide - ENSP00000481721
Ensembl peptide - ENSP00000364203
NCBI entrez gene - 55357     See in Manteia.
OMIM - 609871
RefSeq - XM_017014899
RefSeq - NM_001267571
RefSeq - NM_001267572
RefSeq - NM_018421
RefSeq - XM_011518843
RefSeq Peptide - NP_001254501
RefSeq Peptide - NP_060891
RefSeq Peptide - NP_001254500
swissprot - Q9BYX2
swissprot - A0A024R166
Ensembl - ENSG00000095383
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d2ENSDARG00000071304Danio rerio
 TBC1D2ENSGALG00000001944Gallus gallus
 B1AVH7ENSMUSG00000039813Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UPU7 / TBC1D2B / TBC1 domain family member 2BENSG0000016720239
Q66K14 / TBC1D9B / TBC1 domain family member 9BENSG0000019722618
Q6ZT07 / TBC1D9 / TBC1 domain family member 9ENSG0000010943618
Q0IIM8 / TBC1D8B / TBC1 domain family member 8BENSG0000013313817
O95759 / TBC1D8 / TBC1 domain family member 8ENSG0000020463417
SGSM3 / Q96HU1 / small G protein signaling modulator 3ENSG0000010035916
Q9Y2I9 / TBC1D30 / TBC1 domain family member 30ENSG0000011149010


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0045296 cadherin binding IPI


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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