ENSMUSG00000039813


Mus musculus

Features
Gene ID: ENSMUSG00000039813
  
Biological name :Tbc1d2
  
Synonyms : B1AVH7 / Tbc1d2 / TBC1 domain family member 2A
  
Possible biological names infered from orthology : Q9BYX2 / TBC1 domain family member 2
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: B1
Gene start: 46604390
Gene end: 46650209
  
Corresponding Affymetrix probe sets: 10512791 (MoGene1.0st)   1456792_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081670
Ensembl peptide - ENSMUSP00000103379
NCBI entrez gene - 381605     See in Manteia.
MGI - MGI:2652885
RefSeq - XM_006538050
RefSeq - NM_198664
RefSeq - XM_006538047
RefSeq - XM_006538048
RefSeq - XM_006538046
RefSeq Peptide - NP_941066
swissprot - B1AVH7
Ensembl - ENSMUSG00000039813
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d2ENSDARG00000071304Danio rerio
 TBC1D2ENSGALG00000001944Gallus gallus
 Q9BYX2ENSG00000095383Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3U0J8 / Tbc1d2b / TBC1 domain family member 2B / Q9UPU7*ENSMUSG0000003741039
Q5SVR0 / Tbc1d9b / TBC1 domain family member 9B / Q66K14*ENSMUSG0000003664418
Q3UYK3 / Tbc1d9 / TBC1 domain family member 9 / Q6ZT07*ENSMUSG0000003170917
A3KGB4 / Tbc1d8b / TBC1 domain family member 8B / Q0IIM8*ENSMUSG0000004247317
Q9Z1A9 / Tbc1d8 / Mus musculus TBC1 domain family, member 8 (Tbc1d8), transcript variant 3, mRNA. / O95759* / TBC1 domain family member 8*ENSMUSG0000000313417
Sgsm3 / Q8VCZ6 / Small G protein signaling modulator 3 / Q96HU1*ENSMUSG0000004230316
Q69ZT9 / Tbc1d30 / TBC1 domain family member 30 / Q9Y2I9*ENSMUSG0000005230210


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0043547 positive regulation of GTPase activity ISS
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

 MP:0001566 hyperphosphatemia "abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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