ENSMUSG00000037410


Mus musculus

Features
Gene ID: ENSMUSG00000037410
  
Biological name :Tbc1d2b
  
Synonyms : Q3U0J8 / Tbc1d2b / TBC1 domain family member 2B
  
Possible biological names infered from orthology : Q9UPU7
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.1
Gene start: 90202027
Gene end: 90270804
  
Corresponding Affymetrix probe sets: 10595680 (MoGene1.0st)   1428508_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045413
Ensembl peptide - ENSMUSP00000118947
Ensembl peptide - ENSMUSP00000140684
NCBI entrez gene - 67016     See in Manteia.
MGI - MGI:1914266
RefSeq - XM_011242794
RefSeq - NM_194334
RefSeq Peptide - NP_919315
swissprot - A0A087WRL5
swissprot - Q3U0J8
swissprot - F6W2R3
Ensembl - ENSMUSG00000037410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d2bENSDARG00000061986Danio rerio
 TBC1D2BENSGALG00000003322Gallus gallus
 Q9UPU7ENSG00000167202Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B1AVH7 / Tbc1d2 / TBC1 domain family member 2A / Q9BYX2* / TBC1 domain family member 2*ENSMUSG0000003981337
Q3UYK3 / Tbc1d9 / TBC1 domain family member 9 / Q6ZT07*ENSMUSG0000003170918
Q5SVR0 / Tbc1d9b / TBC1 domain family member 9B / Q66K14*ENSMUSG0000003664417
Q9Z1A9 / Tbc1d8 / Mus musculus TBC1 domain family, member 8 (Tbc1d8), transcript variant 3, mRNA. / O95759* / TBC1 domain family member 8*ENSMUSG0000000313417
A3KGB4 / Tbc1d8b / TBC1 domain family member 8B / Q0IIM8*ENSMUSG0000004247316
Sgsm3 / Q8VCZ6 / Small G protein signaling modulator 3 / Q96HU1*ENSMUSG0000004230313
Q69ZT9 / Tbc1d30 / TBC1 domain family member 30 / Q9Y2I9*ENSMUSG000000523029


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

 MP:0005567 decreased circulating total protein level "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]
Show

Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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