ENSG00000204634


Homo sapiens

Features
Gene ID: ENSG00000204634
  
Biological name :TBC1D8
  
Synonyms : O95759 / TBC1D8 / TBC1 domain family member 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q11.2
Gene start: 101007617
Gene end: 101252866
  
Corresponding Affymetrix probe sets: 204526_s_at (Human Genome U133 Plus 2.0 Array)   221592_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366036
Ensembl peptide - ENSP00000386856
NCBI entrez gene - 11138     See in Manteia.
RefSeq - XM_017003199
RefSeq - NM_001102426
RefSeq - XM_005263863
RefSeq - XM_005263864
RefSeq - XM_011510507
RefSeq - XM_017003198
RefSeq - XM_005263862
RefSeq Peptide - NP_001095896
RefSeq Peptide - NP_001317277
swissprot - O95759
swissprot - J3KQ40
Ensembl - ENSG00000204634
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO018176.1ENSDARG00000104493Danio rerio
 TBC1D8ENSGALG00000016776Gallus gallus
 Q9Z1A9ENSMUSG00000003134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q0IIM8 / TBC1D8B / TBC1 domain family member 8BENSG0000013313852
Q66K14 / TBC1D9B / TBC1 domain family member 9BENSG0000019722651
Q6ZT07 / TBC1D9 / TBC1 domain family member 9ENSG0000010943650
Q9BYX2 / TBC1D2 / TBC1 domain family member 2ENSG0000009538314
Q9UPU7 / TBC1D2B / TBC1 domain family member 2BENSG0000016720214
SGSM3 / Q96HU1 / small G protein signaling modulator 3ENSG0000010035914
Q9Y2I9 / TBC1D30 / TBC1 domain family member 30ENSG0000011149011


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR004182  GRAM domain
 IPR011992  EF-hand domain pair
 IPR035969  Rab-GTPase-TBC domain superfamily
 IPR036009  TBC1D8, PH-GRAM domain 1
 IPR036016  TBC1D8, PH-GRAM domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0008015 blood circulation TAS
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0016020 membrane TAS
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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