ENSG00000133742


Homo sapiens

Features
Gene ID: ENSG00000133742
  
Biological name :CA1
  
Synonyms : CA1 / carbonic anhydrase 1 / P00915
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q21.2
Gene start: 85327608
Gene end: 85379014
  
Corresponding Affymetrix probe sets: 205949_at (Human Genome U133 Plus 2.0 Array)   205950_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430710
Ensembl peptide - ENSP00000429688
Ensembl peptide - ENSP00000429798
Ensembl peptide - ENSP00000429843
Ensembl peptide - ENSP00000430372
Ensembl peptide - ENSP00000430471
Ensembl peptide - ENSP00000430543
Ensembl peptide - ENSP00000430571
Ensembl peptide - ENSP00000430656
Ensembl peptide - ENSP00000430737
Ensembl peptide - ENSP00000486171
Ensembl peptide - ENSP00000443517
Ensembl peptide - ENSP00000430975
Ensembl peptide - ENSP00000430861
Ensembl peptide - ENSP00000392338
Ensembl peptide - ENSP00000427773
Ensembl peptide - ENSP00000427852
Ensembl peptide - ENSP00000428923
Ensembl peptide - ENSP00000429300
NCBI entrez gene - 759     See in Manteia.
OMIM - 114800
RefSeq - NM_001738
RefSeq - NM_001291968
RefSeq - NM_001291967
RefSeq - NM_001164830
RefSeq - NM_001128831
RefSeq - NM_001128830
RefSeq - NM_001128829
RefSeq Peptide - NP_001122303
RefSeq Peptide - NP_001122301
RefSeq Peptide - NP_001122302
RefSeq Peptide - NP_001158302
RefSeq Peptide - NP_001278896
RefSeq Peptide - NP_001278897
RefSeq Peptide - NP_001729
swissprot - E5RHP7
swissprot - E5RH81
swissprot - E5RGU8
swissprot - E5RG81
swissprot - E5RG43
swissprot - E5RFL2
swissprot - P00915
swissprot - V9HWE3
swissprot - E5RFE7
swissprot - E5RJI8
swissprot - E5RJF6
swissprot - E5RII2
swissprot - E5RIF9
swissprot - H0YBE2
swissprot - E5RHS7
Ensembl - ENSG00000133742
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ca2ENSDARG00000014488Danio rerio
 cahzENSDARG00000011166Danio rerio
 Car1ENSMUSG00000027556Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CA13 / Q8N1Q1 / carbonic anhydrase 13ENSG0000018501560
CA2 / P00918 / carbonic anhydrase 2ENSG0000010426760
CA3 / P07451 / carbonic anhydrase 3ENSG0000016487954
CA7 / P43166 / carbonic anhydrase 7ENSG0000016874851
CA5A / P35218 / carbonic anhydrase 5AENSG0000017499049
CA5B / Q9Y2D0 / carbonic anhydrase 5BENSG0000016923949
CA8 / P35219 / carbonic anhydrase 8ENSG0000017853840
CA12 / O43570 / carbonic anhydrase 12ENSG0000007441037
CA14 / Q9ULX7 / carbonic anhydrase 14ENSG0000011829834
CA6 / P23280 / carbonic anhydrase 6ENSG0000013168633
CA9 / Q16790 / carbonic anhydrase 9ENSG0000010715931
CA4 / P22748 / carbonic anhydrase 4ENSG0000016743430


Protein motifs (from Interpro)
Interpro ID Name
 IPR001148  Alpha carbonic anhydrase domain
 IPR018338  Carbonic anhydrase, alpha-class, conserved site
 IPR018442  Carbonic anhydrase, CA1
 IPR023561  Carbonic anhydrase, alpha-class
 IPR036398  Alpha carbonic anhydrase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0015701 bicarbonate transport TAS
 biological_processGO:0035722 interleukin-12-mediated signaling pathway TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004064 arylesterase activity IMP
 molecular_functionGO:0004089 carbonate dehydratase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016836 hydro-lyase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxide
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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