ENSG00000134216


Homo sapiens

Features
Gene ID: ENSG00000134216
  
Biological name :CHIA
  
Synonyms : CHIA / chitinase, acidic / Q9BZP6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.2
Gene start: 111290862
Gene end: 111320566
  
Corresponding Affymetrix probe sets: 220630_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433309
Ensembl peptide - ENSP00000391132
Ensembl peptide - ENSP00000436946
Ensembl peptide - ENSP00000271312
Ensembl peptide - ENSP00000338970
Ensembl peptide - ENSP00000341828
Ensembl peptide - ENSP00000358755
Ensembl peptide - ENSP00000387671
Ensembl peptide - ENSP00000390476
NCBI entrez gene - 27159     See in Manteia.
OMIM - 606080
RefSeq - XM_017001048
RefSeq - NM_001040623
RefSeq - NM_001258001
RefSeq - NM_001258002
RefSeq - NM_001258003
RefSeq - NM_001258004
RefSeq - NM_001258005
RefSeq - NM_021797
RefSeq - NM_201653
RefSeq - XM_006710577
RefSeq - XM_017001047
RefSeq Peptide - NP_001035713
RefSeq Peptide - NP_001244931
RefSeq Peptide - NP_001244934
RefSeq Peptide - NP_068569
RefSeq Peptide - NP_970615
RefSeq Peptide - NP_001244930
RefSeq Peptide - NP_001244932
RefSeq Peptide - NP_001244933
swissprot - H7BXH6
swissprot - Q9BZP6
swissprot - E9PLJ2
swissprot - Q5VUV5
Ensembl - ENSG00000134216
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000031807Gallus gallus
 ENSGALG00000003519Gallus gallus
 CHIAENSGALG00000023760Gallus gallus
 Chia1ENSMUSG00000062778Mus musculus
 Chil3ENSMUSG00000040809Mus musculus
 Chil4ENSMUSG00000063779Mus musculus
 Chil5ENSMUSG00000043873Mus musculus
 Chil6ENSMUSG00000027902Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHIT1 / Q13231 / chitinase 1ENSG0000013306352
OVGP1 / Q12889 / oviductal glycoprotein 1ENSG0000008546544
CHI3L1 / P36222 / chitinase 3 like 1ENSG0000013304841
CHI3L2 / Q15782 / chitinase 3 like 2ENSG0000006488640


Protein motifs (from Interpro)
Interpro ID Name
 IPR001223  Glycoside hydrolase family 18, catalytic domain
 IPR001579  Glycoside hydrolase, chitinase active site
 IPR002557  Chitin binding domain
 IPR011583  Chitinase II
 IPR017853  Glycoside hydrolase superfamily
 IPR029070  Chitinase insertion domain superfamily
 IPR036508  Chitin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000272 polysaccharide catabolic process IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002532 production of molecular mediator involved in inflammatory response IDA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006030 chitin metabolic process NAS
 biological_processGO:0006032 chitin catabolic process NAS
 biological_processGO:0006037 cell wall chitin metabolic process TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response NAS
 biological_processGO:0007586 digestion NAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009620 response to fungus TAS
 biological_processGO:0044245 polysaccharide digestion TAS
 biological_processGO:0090197 positive regulation of chemokine secretion IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003796 lysozyme activity NAS
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0004568 chitinase activity TAS
 molecular_functionGO:0008061 chitin binding TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0030246 carbohydrate binding NAS


Pathways (from Reactome)
Pathway description
Digestion of dietary carbohydrate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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