ENSG00000134443


Homo sapiens

Features
Gene ID: ENSG00000134443
  
Biological name :GRP
  
Synonyms : gastrin releasing peptide / GRP / P07492
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.32
Gene start: 59220168
Gene end: 59230774
  
Corresponding Affymetrix probe sets: 206326_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000256857
Ensembl peptide - ENSP00000397814
Ensembl peptide - ENSP00000431579
Ensembl peptide - ENSP00000434101
Ensembl peptide - ENSP00000389696
NCBI entrez gene - 2922     See in Manteia.
OMIM - 137260
RefSeq - XM_017025714
RefSeq - NM_001012512
RefSeq - NM_001012513
RefSeq - NM_002091
RefSeq - XM_011525933
RefSeq - XM_017025712
RefSeq - XM_017025713
RefSeq Peptide - NP_002082
RefSeq Peptide - NP_001012531
RefSeq Peptide - NP_001012530
swissprot - A0A140VJM7
swissprot - P07492
swissprot - H0Y5C5
swissprot - H0YCH3
Ensembl - ENSG00000134443
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRPENSGALG00000040959Gallus gallus
 GrpENSMUSG00000024517Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000874  Bombesin/neuromedin-B/ranatensin peptide family
 IPR015674  Gastrin releasing peptide


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0036343 psychomotor behavior IEA
 biological_processGO:0043207 response to external biotic stimulus IEA
 biological_processGO:0090277 positive regulation of peptide hormone secretion ISS
 biological_processGO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0034774 secretory granule lumen ISS
 molecular_functionGO:0005102 signaling receptor binding NAS
 molecular_functionGO:0005184 neuropeptide hormone activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000135577 NMBR / P28336 / neuromedin B receptor  / complex / reaction
 ENSG00000126010 GRPR / P30550 / gastrin releasing peptide receptor  / reaction / complex






 

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