ENSG00000126010


Homo sapiens

Features
Gene ID: ENSG00000126010
  
Biological name :GRPR
  
Synonyms : gastrin releasing peptide receptor / GRPR / P30550
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p22.2
Gene start: 16123556
Gene end: 16153021
  
Corresponding Affymetrix probe sets: 207929_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000369643
NCBI entrez gene - 2925     See in Manteia.
OMIM - 305670
RefSeq - NM_005314
RefSeq Peptide - NP_005305
swissprot - P30550
swissprot - X5D7H2
Ensembl - ENSG00000126010
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grprENSDARG00000056620Danio rerio
 GRPRENSGALG00000027960Gallus gallus
 GrprENSMUSG00000031364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NMBR / P28336 / neuromedin B receptorENSG0000013557755
BRS3 / P32247 / bombesin receptor subtype 3ENSG0000010223951
EDNRA / P25101 / endothelin receptor type AENSG0000015161728
EDNRB / P24530 / endothelin receptor type BENSG0000013616028
GPR37 / O15354 / G protein-coupled receptor 37ENSG0000017077523
O60883 / GPR37L1 / G protein-coupled receptor 37 like 1ENSG0000017007521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001556  Bombesin receptor-like
 IPR001966  Gastrin-releasing peptide receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0036343 psychomotor behavior IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043207 response to external biotic stimulus IEA
 biological_processGO:0061744 motor behavior IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008188 neuropeptide receptor activity IEA
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity TAS
 molecular_functionGO:0042923 neuropeptide binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000197696 NMB / P08949 / neuromedin B  / complex / reaction
 ENSG00000134443 GRP / P07492 / gastrin releasing peptide  / reaction / complex






 

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