ENSG00000170075


Homo sapiens

Features
Gene ID: ENSG00000170075
  
Biological name :GPR37L1
  
Synonyms : GPR37L1 / G protein-coupled receptor 37 like 1 / O60883
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 202122858
Gene end: 202133592
  
Corresponding Affymetrix probe sets: 1556155_at (Human Genome U133 Plus 2.0 Array)   1558189_a_at (Human Genome U133 Plus 2.0 Array)   207055_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356251
NCBI entrez gene - 9283     See in Manteia.
OMIM - 617630
RefSeq - NM_004767
RefSeq Peptide - NP_004758
swissprot - O60883
Ensembl - ENSG00000170075
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr37l1aENSDARG00000006079Danio rerio
 gpr37l1bENSDARG00000056774Danio rerio
 GPR37L1ENSGALG00000000607Gallus gallus
 Q99JG2ENSMUSG00000026424Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR37 / O15354 / G protein-coupled receptor 37ENSG0000017077547
EDNRB / P24530 / endothelin receptor type BENSG0000013616021
EDNRA / P25101 / endothelin receptor type AENSG0000015161720
NMBR / P28336 / neuromedin B receptorENSG0000013557716
GRPR / P30550 / gastrin releasing peptide receptorENSG0000012601016
BRS3 / P32247 / bombesin receptor subtype 3ENSG0000010223914


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR003909  G protein-coupled receptor 37 orphan
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IDA
 biological_processGO:0021940 positive regulation of cerebellar granule cell precursor proliferation IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IEA
 biological_processGO:0048712 negative regulation of astrocyte differentiation IEA
 biological_processGO:1903206 negative regulation of hydrogen peroxide-induced cell death IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IDA
 molecular_functionGO:0036505 prosaposin receptor activity IDA
 molecular_functionGO:0042277 peptide binding IPI


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000197746 PSAP / P07602 / prosaposin  / complex / reaction






 

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